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BigFiRSt: A Software Program Using Big Data Technique for Mining Simple Sequence Repeats From Large-Scale Sequencing Data

BackgroundSimple Sequence Repeats (SSRs) are short tandem repeats of nucleotide sequences.It has been shown that SSRs are associated with human diseases and are of medical relevance.Accordingly, a variety of computational methods have been proposed to mine SSRs from genomes.Conventional methods rely on a high-quality complete genome to identify SSR

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Low budget analysis of Direct-To-Consumer genomic testing familial data [v1; ref status: indexed, http://f1000r.es/Nmz0oW]

Direct-to-consumer (DTC) genetic testing is a recent commercial endeavor that allows the general public to access personal genomic data.The growing availability of personal genomic data has in turn stimulated the development of non-commercial tools for DTC data analysis.Despite this new wealth of public resources, no systematic research has been ca

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High prevalence of SARS-CoV-2 antibodies and low prevalence of SARS-CoV-2 RNA in cats recently exposed to human cases

Abstract Background The primary objective of this cross-sectional study, conducted in Québec and Bristish Columbia (copyright) between February 2021 and January 2022, was to measure the prevalence of viral RNA in oronasal and rectal swabs and serum antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) amongst cats living in ho

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